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Methods/ResourceReagentSpeciesCell line / ConditionNumber of interactions
PARIS (Cell Host & Microbe, 2018)AMTZikain vivo2,764
in vitro1,470
SPLASH (NC, 2019)biotinylated psoralenZikain virion400
in cell400
Denguein virion400
in cell400
SPLASH (NC, 2022)biotinylated psoralenSARS-CoV-2in vivo424
SPLASH (NC, 2021)Psoralen-PEG3-BiotinSARS-CoV-2cell47,295
lysate78,715
virion139,941
PARIS2 (NC, 2021)amotosalen HumanHEK293 in vivo snoRNA187,689
HEK293 in vivo mRNA331,803
MouseC57BL/6J brain in vivo snoRNA63,000
C57BL/6J brain in vivo mRNA446,421
SHARC (NC, 2022)DPIHumanHeLa in vivo 5mM RNaseR0h53,411
HeLa in vivo 5mM RNaseR2h2,066
HeLa in vivo 5mM RNaseR12h9,050
HeLa in vivo 12.5mM RNaseR0h19,544
HeLa in vivo 12.5mM RNaseR2h10,536
HeLa in vivo 12.5mM RNaseR12h5,217
HeLa in vivo 12.5mM RNaseR24h61
HeLa in vivo 25mM RNaseR0h138,166
HeLa in vivo 25mM RNaseR2h53,615
HeLa in vivo 25mM RNaseR24h1,917
CRIC-seq (Mol. Cell, 2023)formaldehydeHumanHeLa hnRNPA1_IP_pCp_plus2,087,126
HeLa PTBP1_IP_pCp_plus4,082,863
HeLa SRSF1_IP_pCp_plus1,077,827
PARIS (GPB, 2022)AMTHumanin vivo PC98,609
in vivo PC9 gefitinib-R10,401
in vivo PC9 AZD9291-R7,198
KARR-seq (NBT, 2024)formaldehydeMousemESC_G11,168,142
mESC_G31,227,779
mESC_G5644,462
mESC_G7458,351
mESC_invivo_G1857,802
mESC_refold_G1789,202
HumanHEK293T_invivo_G11,369,972
HEK293T_refold_G1942,422
HepG2_invivo_G1647,932
HepG2_refold_G1917,682
HepG2_siControl_G1739,234
HepG2_siDDX3X_G1695,100
HepG2_CHX_G11,020,981
HepG2_HT_G11,084,495
HepG2_TotalRNA_G192,547
K562_invivo_G11,652,573
K562_refold_G11,271,777
K562_Nuclear_G11,326,026
K562_siControl_G12,082,184
K562_siYBX3_G12,248,864
K562_siSRSF1_Total_G11,611,397
K562_siSRSF1_Nuclear_G11,249,875
K562_Arsenite_Total_G11,432,362
K562_Arsenite_Nuclear_G11,306,850
K562_lowXL_G12,115,061
K562_noXL_G13,209,748
A549_Mock_G12,546,888
A549_RSV_G11,509,324
A549_VSV_G1873,474
PARIS (Cell Rep., 2024)AMTIAVWSN invivo832
WSN invirio1,712
COMRADES (Mol. Cell, 2020)Psoralen-TEG azideSARS-CoV-2control5,046
sample7,432

Methods/ResourceSpeciesCell line / ConditionNumber of interactions
PARIS (Cell, 2016)HumanHEK293T25,815
HeLa (high RNase)25,549
HeLa (low RNase)20,328
MousemESC29,514
MARIO (NC, 2016)MouseMEF7,167
mESC (one protein)99,284
mESC (multi proteins)37,441
SPLASH (Nature, 2013)HumanhESC3,345
SPLASH (Mol. Cell, 2016)HumanHeLa5,799
LCL4,213
RA1,770
LIGR-seq (Mol. Cell, 2016)HumanHEK293T641
RIA-seq (Cell, 2014)HumanKeratinocytes (TINCR)3,575
RAP-RNA (Cell, 2016)MousemESC (MALAT1)495
RAP-RNA (Cell, 2014)MousemESC (U1 snRNA)12,278
CLASH (Cell, 2013)HumanHEK293 (miRNAs)18,505
CLASH (PNAS, 2011)YeastBY4741 (miRNAs)253
PARIS2 (NC, 2021)HumanHEK293 in vivo snoRNA42,057
HEK293 in vivo mRNA74,997
MouseC57BL/6J brain in vivo snoRNA11,596
C57BL/6J brain in vivo mRNA77,981
SHARC (NC, 2022)HumanHeLa in vivo 5mM RNaseR0h18,497
HeLa in vivo 5mM RNaseR2h1,839
HeLa in vivo 5mM RNaseR12h6,041
HeLa in vivo 12.5mM RNaseR0h6,646
HeLa in vivo 12.5mM RNaseR2h6,874
HeLa in vivo 12.5mM RNaseR12h3,930
HeLa in vivo 12.5mM RNaseR24h304
HeLa in vivo 25mM RNaseR0h52,140
HeLa in vivo 25mM RNaseR2h16,147
HeLa in vivo 25mM RNaseR24h2,433
CRIC-seq (Mol. Cell, 2023)HumanHeLa hnRNPA1_IP_pCp_plus90,410
HeLa PTBP1_IP_pCp_plus528,431
HeLa SRSF1_IP_pCp_plus211,915
PARIS (GPB, 2022)Humanin vivo PC935,031
in vivo PC9 gefitinib-R30,630
in vivo PC9 AZD9291-R39,227
KARR-seq (NBT, 2024)MousemESC_G1182,663
mESC_G3194,758
mESC_G594,065
mESC_G771,738
mESC_invivo_G1122,530
mESC_refold_G162,869
HumanHEK293T_invivo_G1162,569
HEK293T_refold_G1121,360
HepG2_invivo_G1103,055
HepG2_refold_G189,564
HepG2_siControl_G1135,405
HepG2_siDDX3X_G1136,192
HepG2_CHX_G1141,922
HepG2_HT_G1145,285
HepG2_TotalRNA_G111,097
K562_invivo_G1180,697
K562_refold_G1112,046
K562_Nuclear_G186,847
K562_siControl_G1144,897
K562_siYBX3_G1159,259
K562_siSRSF1_Total_G1139,191
K562_siSRSF1_Nuclear_G182,409
K562_Arsenite_Total_G1144,923
K562_Arsenite_Nuclear_G1137,252
K562_lowXL_G1256,074
K562_noXL_G1349,369
A549_Mock_G1137,401
A549_RSV_G169,697
A549_VSV_G142,915
PARIS (Cell Rep., 2024)IAVWSN invivo41
WSN invirio5,045
SPLASH (Nat Microbiol., 2019)IAVin virio4,041